Poon, Randy Y. C. (Hrsg.)
Polyploidization and Cancer
Beschreibung
Limiting genome replication to once per cell cycle is vital for maintaining genome
stability. Although polyploidization is of physiologically importance for several
specialized cell types, inappropriate polyploidization is believed to promote aneuploidy
and transformation. A growing body of evidence indicates that the surveillance
mechanisms that prevent polyploidization are frequently perturbed in cancers.
Progress in the past several years has unraveled some of the underlying principles
that maintain genome stability. This book brings together leaders of the field to overview
subjects relating to polyploidization and cancer.
stability. Although polyploidization is of physiologically importance for several
specialized cell types, inappropriate polyploidization is believed to promote aneuploidy
and transformation. A growing body of evidence indicates that the surveillance
mechanisms that prevent polyploidization are frequently perturbed in cancers.
Progress in the past several years has unraveled some of the underlying principles
that maintain genome stability. This book brings together leaders of the field to overview
subjects relating to polyploidization and cancer.
Produktdetails
| ISBN/GTIN | 978-1-4419-6199-0 |
|---|---|
| Seitenzahl | 151 S. |
| Kopierschutz | mit Wasserzeichen |
| Dateigröße | 3187 Kbytes |