Retinoblastoma

Retinoblastoma is the most common cancer of the eye in children. Although it is a rare neoplasm, there are many features that make this malignancy unique. Nationally, the incidence is approximately 4 million children per year. 90% of these cases occur in children under 5 and more than 90% will be cured. The resulting effects of the treatment can be blindness, quality of life after survival, and/or reduced life span. However in the last few years, significant advances have been made, including the development of the first mouse models (2004).