Hematopoietic Stem Cell Biology

Hematopoietic Stem Cell Biology is the newest installment in the Stem Cell Biology and Regenerative Medicine series, to which it adeptly contributes as it offers a selection of carefully chosen topics so that the readers can understand recent advances in the field of the hematopoietic stem cells and hemato/lymphopoiesis. Each chapter is not a simple review of the topic, but rather an in-depth insight, which allows the reader to attain a multifaceted knowledgebase on hematopoietic stem cells. The chapters, which are authored by the leading experts in the field, cover characteristics of the hematopoietic stem cells at the cellular and molecular levels, offers details in regulatory mechanisms of differentiation mechanisms of hematopoietic stem cells to more mature blood cell, and discusses abnormal hematopoiesis that leads to leukemia. Hematopoietic Stem Cell Biology serves the inquiring minds of researchers, graduate students and post doctorate fellows as it expertly addresses the ever-growing field of hematopoietic stem cells and hemato/lymphopoiesis. This book is written by experts in the field of hematopoietic stem cell biology and lymphocyte development in order to overview recent advances in the field. Prospective isolation of various progenitors and stem cells enables us to understand self-renewal mechanisms of stem cells as well as regulation of hematopoiesis. Furthermore, the importance of extrinsic factors has been emphasized recently. This volume concisely describes our current understanding of normal hemato/lymphopoiesis as well as abnormal hematopoiesis, which may lead to leukemia.