Paraoxonases in Inflammation, Infection, and Toxicology

The pivotal role of the Paraoxonases (PON) family in a variety of inflammatory diseases, e.g. atherosclerosis, in preventing the toxicity of organophosphorus insecticides and nerve agents and a variety of other compounds has made them an interesting target for both clinicians and scientists alike. Research into the paraoxonase (PON) family of enzymes (PON1, PON2 and PON3) has increased exponentially over the last five years especially following the initiation of paraoxonase conferences.