Diabetes, Insulin and Alzheimer's Disease

This volume brings together experts from basic and clinical science to provide a broad survey of the role of insulin in the brain, and to discuss the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease. Each author has greatly furthered our understanding of the relationships among insulin, diabetes, and Alzheimer s disease, moving us far beyond the belief that the brain is an insulin-insensitive organ. Given the recent pandemic of conditions associated with insulin resistance, it is imperative that we achieve a comprehensive knowledge of the mechanisms through which insulin resistance affects brain function in order to develop therapeutic strategies to address these effects.