CONTENTS DiePharmazie 09/1999 Review Mück, W.: Quantitative anaysis of pharmacokinetic study samples by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) (Review) Original Articles Bleeker, C.; Kunick, C.: Naphthannelated azepinones: synthesis and antitumor activity Bukowski, L.; Janowiec, M.; Zwolska-Kwiek, Z.; Andrzejczyk, Z.: Synthesis and some reactions of 2-acetylimidazo[4,5-b]pyridine. Antituberculotic activity of the obtained compounds Görlitzer, K.; Weltrowski, I.-M.; Wray, V.; Schumann, R.: Bromination products of morphine (in German) Meise, W.; Onusseit, O.; Clemens, M.: Synthesis of isoquino[1,2-a][2]benzazepines and biochemical testing of isomeric homoberbines and related papaverine-derivatives on the inhibition of phosphodiesterases (in German) Abdel-Rahman, R. M.; Morsy, J. M.; El-Edfawy, S.; Amine, H. A.: Synthesis of some new heterobicyclic nitrogen systems bearing the 1,2,4-triazine moiety as anti-HIV and anti-cancer drugs, part II Yamada, T.; Yamamoto, A.; Fujioka, M.; Miyagi, M.; Saito, N.; Imai, I.; Otagiri, M.: Characterization of urinary metabolites of a new benzofuroquinoline derivative 3,9-bis(N,N-dimethylcarbamoyloxy)-5 H-benzofuro[3,2-c]- quinoline-6-one (KCA-098) in dogs Baweja, J. M.; Misra, A. N.: Modified guar gum as film former El-Ridy, M. S.; Khalil, R. M.: Free versus liposome-encapsulated lignocaine hydrochloride topical applications Salerno, L.; Sorrenti, V.; Guerrera, F.; Sarvŕ, M. C.; Siracusa, M. A.; Di Giacomo, C.; Vanella, A.: N-subsituted-imidazoles as inhibitors of nitric oxide synthase: a preliminary screening Gupton, J. T.; Burham, B. S.; Byrd, B. D.; Krumpe, K. E.; Stoked, C.; Shuford, J.; Winkle, S.; Webb, T.; Warren, A. E.; Barnes, C.R.; Henry, J.; Hall, I. H.: The cytotoxicity and mode of action of 2,3,4-trisubstituted pyrroles and related derivatives in human Tmolt4 leukemia cells Andricopulo, A. D.; Yunes, R. A.; Cechinel Filho, V.; Nunes, R. J.; Frazer, J. W.; Cordes, E. H.: Development of a predictive statistical model for the analgesic activity of a family of imides Short communications Lankau, H.-J.; Menzer, M.; Rostock, A.; Arnold, Th.; Rundfeldt, Ch.; Unverferth, K.: Synthesis and anticonvulsant activity of new 4-aminopyrazoles and 5-aminopyrazol-3-ones De Villiers, M. M.; Bergh, J. J.: Reverse-phase liquid chromatographic UV method for analysis of hexoprenaline sulphate and selection of chromatographic conditions suitable for multi-ß-agonist analysis Lahl, H.; Azizkabiri, A.; Ständer, M.; Unterhalt, B.: Determination of elements in the skin of psoriatic and non-psoriatic patients (in German) Fang, J.-Y.; Sung, K. C.; Chien, S.-C.: Influence of coupling medium on in vitro sonophoresis of clobetasol 17-propionate Bezáková, L.; Psenák, M.; Karting, T.: Effect of dianthrones and their precursors form Hypericum perforatum L. on lipoxygenase activity Melzig, M. F.; Löser, B.; Lobitz, G. O.; Tamayo-Castillo, G.; Merfort, I.: Inhibition of granulocyte elastase activity by caffeic acid derivatives Drsata, J.; Netopilová, M.; Tolman, V.: Stereoisomers of 4-fluoroglutamic acid: influence on Escherichia coli glutamate decarboxylase Mucaji, P.; Grancai, D.; Nagy, M.; Budesinsky, M.; Ubik, K.: Triterpenoid saponins from Cynara cardunculus L.