All research papers in this issue were presented during the 6th Conference on Retrometabolism Based Drug Design and Targeting, June 3-6, 2007, Göd, Hungary.

Wu WM, Wu J, Mori N, Buchwald P, Bodor N : Stereoisomers of N-substituted soft anticholinergics and their zwitterionic metabolite based on glycopyrrolate - syntheses and pharmacological evaluations
doi:10.1691/ph.2008.7775

Tokés B, Száva J, Dusa S, Ferencz L, Vintila A, Donáth-Nagy G: The importance, design and modeling of biodegradable complexats. An extension of the structure-soft character relations
doi:10.1691/ph.2008.7772

Masungi C, Mensch J, Van Dijck A, Borremans C, Willems B, Mackie C, Noppe M, Brewster ME: Parallel Artificial Membrane Permeability Assay (PAMPA) combined with a 10-day multiscreen Caco-2 cell culture as a tool for assessing new drug candidates
doi:10.1691/ph.2008.7327

Patthy M, Seres G, Tóth-Sarudy Č, Hazai I, Pallagi I, Simay A, Bodor N: Determination of estredox, a compound with sustained estradiol function, and its impurity profile by HPLC
doi:10.1691/ph.2008.7321

Brewster ME, Vandecruys R, Verreck G, Peeters J: Supersaturating drug delivery systems: effect of hydrophilic cyclodextrins and other excipients on the formation and stabilization of supersaturated drug solutions
doi:10.1691/ph.2008.7326

Hidvégi E, Hideg ZS, Somogyi GP: Different reactivities of amphetamines with N-methyl-bis(trifluoroacetamide) in heated gas chromatographic injectors
doi:10.1691/ph.2008.7328

Latere Dwan'Isa JP, Rouxhet L, Brewster ME, Préat V, Ariën A: Spontaneously self-assembled micelles from poly(ethylene glycol)-b-poly(e-caprolactone-co-trimethylene carbonate) for drug solubilization
doi:10.1691/ph.2008.7324

Morimoto K, Fukushi N, Chono S, Seki T, Tabata Y: Spermined dextran, a cationized polymer, as absorption enhancer for pulmonary application of peptide drugs
doi:10.1691/ph.2008.7323

Tack F, Noppe M, Van Dijck A, Dekeyzer N, Van Der Leede BJ, Bakker A, Wouters W, Janicot M, Brewster ME: Delivery of a DNAzyme targeting c-myc to HT29 colon carcinoma cells using a gold nanoparticulate approach
doi:10.1691/ph.2008.7325

Mori N, Yokooji T, Murakami T: Fate of quinidine, a P-glycoprotein substrate, in the gastrointestinal tract after oral administration in rats
doi:10.1691/ph.2008.7771

Bocca N, Pileggi A, Molano RD, Marzorati S, Wu W, Bodor N, Ricordi C, Buchwald P: Soft corticosteroids for local immunosuppression: exploring the possibility for the use of loteprednol etabonate for islet transplantation
doi:10.1691/ph.2008.7774

Vincze Z, Brugos B: Does impairment of renal and hepatic function influence the metabolism of thrombolytics in patients with myocardial infarction?
doi:10.1691/ph.2008.7773